Clinical pharmacokinetics and pharmacodynamics of mycophenolate in ...
It is metabolised in the liver, gastrointestinal tract and kidney by uridine diphosphate gluconosyltransferases (UGTs). 7OMPAglucuronide (MPAG) is the major metabolite of MPA. MPAG is usually present in the plasma at 20 to 100fold higher concentrations than MPA, but it is not pharmacologically active.